Chiara Riganti Selected Research

Heme (Haem)

2/2022	Inhibition of Heme Export and/or Heme Synthesis Potentiates Metformin Anti-Proliferative Effect on Cancer Cell Lines.
10/2021	Endothelial Heme Dynamics Drive Cancer Cell Metabolism by Shaping the Tumor Microenvironment.
1/2021	The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation.

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Chiara Riganti Research Topics

Disease

127	Neoplasms (Cancer) 05/2024 - 12/2002
16	Malignant Mesothelioma 02/2024 - 06/2004
15	Breast Neoplasms (Breast Cancer) 12/2023 - 11/2011
14	Colonic Neoplasms (Colon Cancer) 03/2015 - 01/2005
13	Hypoxia (Hypoxemia) 01/2023 - 11/2009
13	Osteosarcoma (Osteogenic Sarcoma) 01/2023 - 12/2010
11	Glioblastoma (Glioblastoma Multiforme) 01/2019 - 11/2013
8	Mesothelioma 02/2024 - 06/2004
8	Pancreatic Neoplasms (Pancreatic Cancer) 12/2023 - 01/2017
6	Triple Negative Breast Neoplasms 11/2023 - 10/2018
6	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2023 - 05/2020
6	Lung Neoplasms (Lung Cancer) 08/2023 - 01/2019
5	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 10/2023 - 10/2012
5	Neoplasm Metastasis (Metastasis) 08/2023 - 12/2010
5	Cardiotoxicity 09/2022 - 12/2002
4	Colorectal Neoplasms (Colorectal Cancer) 02/2024 - 01/2020
4	Adenocarcinoma 12/2023 - 01/2017
4	Inflammation (Inflammations) 12/2023 - 11/2017
3	Melanoma (Melanoma, Malignant) 05/2024 - 01/2020
3	Carcinoma (Carcinomatosis) 12/2023 - 07/2005
2	Hematologic Neoplasms (Hematological Malignancy) 10/2023 - 10/2019
2	Alzheimer Disease (Alzheimer's Disease) 01/2023 - 12/2020
2	Disease Progression 05/2021 - 05/2021

Drug/Important Bio-Agent (IBA)

48	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2023 - 12/2002
28	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 03/2023 - 11/2009
25	Proteins (Proteins, Gene)FDA Link 02/2024 - 03/2009
11	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2018 - 09/2003
9	EnzymesIBA 12/2023 - 11/2009
9	Mevalonic Acid (Mevalonate)IBA 12/2023 - 12/2010
9	AsbestosIBA 08/2023 - 06/2004
9	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2022 - 02/2016
8	Biomarkers (Surrogate Marker)IBA 12/2023 - 01/2020
8	LipidsIBA 10/2023 - 12/2017
8	Zoledronic Acid (Zometa)FDA Link 01/2022 - 12/2010
7	Cisplatin (Platino)FDA LinkGeneric 02/2024 - 01/2018
7	CholesterolIBA 12/2023 - 01/2011
7	Antineoplastic Agents (Antineoplastics)IBA 10/2023 - 07/2005
7	Transcription Factors (Transcription Factor)IBA 08/2023 - 06/2007
7	AntioxidantsIBA 03/2021 - 09/2011
7	Liposomes (Liposome)IBA 12/2020 - 06/2011
7	AnthracyclinesIBA 02/2019 - 12/2002
6	Phosphotransferases (Kinase)IBA 02/2024 - 03/2009
6	carbonic anhydrase XIIIBA 11/2022 - 03/2015
6	Lipid NanoparticlesIBA 06/2022 - 07/2014
6	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 07/2006
6	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2021 - 07/2013
5	ThiosemicarbazonesIBA 12/2023 - 01/2018
5	Glucose (Dextrose)FDA LinkGeneric 10/2023 - 12/2020
5	LigandsIBA 03/2022 - 10/2012
5	multidrug resistance-associated protein 1IBA 05/2020 - 10/2011
5	NF-kappa B (NF-kB)IBA 01/2020 - 09/2003
5	Temozolomide (Temodar)FDA LinkGeneric 01/2019 - 11/2013
4	Gemcitabine FDA Link 12/2023 - 12/2020
4	Protein Isoforms (Isoforms)IBA 08/2022 - 06/2007
4	Small Interfering RNA (siRNA)IBA 02/2022 - 08/2008
4	Nitric Oxide Synthase (NO Synthase)IBA 11/2009 - 06/2004
3	Mechanistic Target of Rapamycin Complex 2IBA 05/2024 - 01/2017
3	CalreticulinIBA 02/2024 - 01/2018
3	ProdrugsIBA 12/2023 - 03/2017
3	Terpenes (Terpenoids)IBA 12/2023 - 01/2015
3	sigma-2 receptorIBA 12/2023 - 01/2017
3	Oxygen (Dioxygen)IBA 01/2023 - 12/2002
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2023 - 11/2014
3	ProteomeIBA 01/2023 - 03/2015
3	Messenger RNA (mRNA)IBA 08/2022 - 01/2020
3	MicroRNAs (MicroRNA)IBA 08/2022 - 03/2022
3	Glutamine (L-Glutamine)FDA Link 03/2022 - 11/2017
3	Heme (Haem)IBA 02/2022 - 01/2021
3	CytokinesIBA 03/2021 - 09/2003
3	Fatty Acids (Saturated Fatty Acids)IBA 12/2020 - 11/2013
3	Adenosine Triphosphate (ATP)IBA 01/2019 - 10/2013
3	liposomal doxorubicin (Doxil)FDA Link 09/2014 - 01/2011
3	Crocidolite Asbestos (Blue Asbestos)IBA 09/2011 - 06/2004
2	carfilzomibIBA 02/2024 - 01/2018
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 02/2024 - 12/2020
2	CarbonIBA 12/2023 - 01/2021
2	Hyaluronic Acid (Hyaluronan)IBA 12/2023 - 01/2019
2	EndocannabinoidsIBA 12/2023 - 02/2020
2	sigma Receptors (sigma Receptor)IBA 12/2023 - 12/2021
2	CannabinoidsIBA 12/2023 - 02/2020
2	CateninsIBA 11/2023 - 11/2013
2	Drug CombinationsIBA 10/2023 - 12/2010
2	idelalisibIBA 10/2023 - 06/2021
2	Immune Checkpoint InhibitorsIBA 10/2023 - 12/2021
2	glabratephrinIBA 03/2023 - 01/2022
2	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2023 - 01/2021
2	Adenosine Triphosphatases (ATPase)IBA 11/2022 - 10/2012
2	IntegrinsIBA 11/2022 - 01/2017
2	Thymidylate SynthaseIBA 08/2022 - 08/2022
2	Pemetrexed (MTA)FDA Link 08/2022 - 02/2022
2	calcium phosphateIBA 06/2022 - 11/2021
2	Vitamin D FDA LinkGeneric 01/2022 - 01/2020
2	SolutionsIBA 12/2021 - 01/2021
2	Amino Acids FDA Link 12/2021 - 12/2020
2	MetalsIBA 12/2021 - 01/2018
2	Hypoxia-Inducible Factor 1IBA 06/2021 - 01/2020

Therapy/Procedure

40	Therapeutics 05/2024 - 06/2008
32	Drug Therapy (Chemotherapy) 10/2023 - 03/2009
5	Immunotherapy 12/2021 - 07/2012
2	Radiotherapy 12/2021 - 12/2017